HA plays an important role during the cell entry of influenza viruses.
Influenza A viruses belong to the Orthomyxoviridae family they are characterized by a unique genome structure with a single-negative RNA strand, which codifies, among others, for two transmembrane proteins: hemagglutinin (HA) and neuraminidase (NA). In less than a month the virus spread worldwide and on Jthe World Health Organization (WHO) declared the start of the first 21st century influenza pandemic. During April 2009, the number of atypical pneumonia cases increased in Mexico City’s hospitals and spread to almost all boroughs in the city these cases were related to a new influenza A (H1N1) virus strain that was identified as the etiological agent.
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